Optigen Testing

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bynbrig	Optigen Testing	Lead	[-]
Posts: 46 (28 September, 2006 21:54:57) Reply Quote More My Recent Posts Message Me Connection Blocking Invite Ignore User's Posts	Tags : None I'm thinking of getting an Optigen test on my Labrador bitch. It seems like a good idea, I have not bred from her as of yet. She has 2 clear eyes certs and a low hip score but has a shadow in her breeding about 2 gens back. Anybody out there, had this test performed? Any info much appreciated. Thanks Sue
FTNick	Re: Optigen Testing	#1	[-]
Posts: 86 ( 6 October, 2006 21:27:04) Reply Quote More My Recent Posts Message Me Connection Blocking Invite Ignore User's Posts	I have had this test done on a couple of my dogs, the first was a dog that I have at Stud I noticed that in the BRS it was reported that my dogs father had sired 2 pups that had been diagnosed with PRA, this means that my dogs father had to be a carrier, I felt that I was not prepared to stand a dog at stud unless I was aware of his status, as it was he came back A1 so I can relax, I am not sure what my reaction would have been if he had come back B1 (Carrier), I subsequently had a pup exported to europe, the buyer required the pup to be tested before export, again A1. At a FT the other day I was talking to some very well known breeders, I started the conversation because I have a good Golden standing at stud that has clear eyes last test date he was 7, as he is now 8 I was asking weathe they advise keeping the tests up as his copy book would be bloted is he fails and dogs like humans get eye problems as they get older due to age. The people informed me that they do not test their dogs after the 5th year and from now on they intended to just do a normal eye test at 12 months old and then do the optigen test. NickC
Julie Cramond	Re: Optigen Testing	#2	[-]
Posts: 224 (10 October, 2006 09:17:32) Reply Quote More My Recent Posts Message Me Connection Blocking Invite Ignore User's Posts	Hi Sue, I have all my labs Optigen tested for PRA, regardless of yearly clear eye certificates, as PRA has a late onset. Until earlier this year blood was taken and the DNA sent to the US, but nowadays a cheek swab is only required in Australia. Naturally same price, LOL.
bynbrig	Re: Optigen Testing	#3	[-]
Posts: 46 (11 October, 2006 22:11:56) Reply Quote More My Recent Posts Message Me Connection Blocking Invite Ignore User's Posts	Thanks Nick and Julie for your replies. Nick! how did you send the blood test over? I have spoken to my Vets, Margaret Collins, at Codford. They have never done this test before. Looking at the website, did you send it midweek in a polyform with icepacks to the Germany address? I would be very interested in your Stud dog if he has had a clear Optigen test performed. Has he got Sam or Fir? Julie, Hope you had a good time with Lainee and David They are good friends of ours. sue
Julie Cramond	Re: Optigen Testing	#4	[-]
Posts: 224 (13 October, 2006 10:06:04) Reply Quote More My Recent Posts Message Me Connection Blocking Invite Ignore User's Posts	We sure did have a great time with Lainee and David. I greatly enjoyed hearing about their UK visit. Good luck with your test. I found Optigen very efficient.
FTNick	Re: Optigen Testing	#5	[-]
Posts: 86 (15 October, 2006 21:15:50) Reply Quote More My Recent Posts Message Me Connection Blocking Invite Ignore User's Posts	Sue Sorry for the delay in replying but have been away trialing, the instructions as to doing the optigen test are on the optigen web site, the key fact is that your vet has to place the blood in purple tubes so that the blood does not coagulate when you paqy for the test on the web you have a form that is sent with the blood to a lab in Holland they extract the DNA ans then send this to Cornell (Optigen) for the test, Margret Collins should have no problemswith this, if she does my vet isn Salisbury can do it. The dog that the blood is extracted has to have id either microchip or dna I also get the vet to send the blood so that there is an audit trail from dog to lab. Nick
bynbrig	Re: Optigen Testing	#6	[-]
Posts: 46 (27 October, 2006 22:26:44) Reply Quote More My Recent Posts Message Me Connection Blocking Invite Ignore User's Posts	Thanks Nick. for info you have provided, it has helped me a great deal. Looks like I should get my bitch chipped first before the test. Can you email me details of your studs. I'm looking at Riversway as they have a clear test also. However my bitch has more than enough Remus. I need an outcross without any Sam. Many thanks Sue
FTNick	Re: Optigen Testing	#7	[-]
Posts: 86 (27 October, 2006 23:04:06) Reply Quote More My Recent Posts Message Me Connection Blocking Invite Ignore User's Posts	Sue Look at my web site www.gospelash-retrievers.co.uk I have not updated it yet but Burt (Gospelash Gamefinder) won a novice trial last week, his litter brother (Gospelash Genius)was second and won guns choice, I substituted Gospelash Bobby for a trial that was on Saturday and he was 3rd first time out, Gospelash Genius went on to win the URC Novice trial on Tuesday so a good week for my bred dogs. Nick
berrybrae3	Re: Optigen Testing	#8	[-]
Posts: 44 (21 November, 2006 18:26:25) Reply Quote More My Recent Posts Message Me Connection Blocking Invite Ignore User's Posts	HI there could anyone be confirm that FTCH Aughacasla Sam of Drakeshead was a carrier. I was told this but he hasnt been tested so how would you find out? Andy Berrybraegundogs
Dutchfield	Re: Optigen Testing	#9	[-]
Posts: 146 (22 November, 2006 08:32:21) Reply Quote More My Recent Posts Message Me Connection Blocking Invite Ignore User's Posts	Hi Andy, The gen for PRA is given to the offspring recessive Even if the one of the parents is not tested, by the testresults of the offspring you can tell something about the parent without the testresult.In the link you can find a scheme to make it more clear to you. on www.retriever.biz Than in the part labradore,than PRA, than down the page there is a article of mrs Ommerli. It is in German but the scheme is clear to understand. You can solve the rest out yourself I think. Let me know if it doesnt work. Regards, Mike
Amanda	Re: Optigen Testing	#10	[-]
Posts: 84 (24 November, 2006 11:03:26) Reply Quote More My Recent Posts Message Me Connection Blocking Invite Ignore User's Posts	Breeding Strategies for prcd-PRA Test: www.optigen.com/opt9_test_prcdprabs.html They also have a Narcolepsy (NARC) Test: www.optigen.com/opt9_test_narc.html
Evelyn	Re: Optigen Testing	#11	[-]
Posts: 57 (11 December, 2006 18:10:42) Reply Quote More My Recent Posts Message Me Connection Blocking Invite Ignore User's Posts	hi i am a great fan of optigen testing. i am organising sampling tests (not earning any money) just for the race. you can save 20% + 5% filling the form online next one is at the 1. of jan. next 4. feb if i can help you just feel free to ask evelyn@halfman.de lg evelyn
MattA99	Re: Optigen Testing	#12	[-]
Posts: 906 (11 December, 2006 18:37:25) Reply Quote More My Recent Posts Message Me Connection Blocking Invite Ignore User's Posts	Evelyn, Are you just organising for Germany, or is the UK included? Matt
canburne	Re: Optigen Testing	#13	[-]
Posts: 474 (11 December, 2006 19:16:00) Reply Quote More My Recent Posts Message Me Connection Blocking Invite Ignore User's Posts	I have just posted this in the Misc. section - I wonder if the DNAtag screen is the same as or equivalent to the optigen test? p211.ezboard.com/fgundogandbirddogforumsfrm19.showMessage?topicID=259.topic
Evelyn	Re: Optigen Testing	#14	[-]
Posts: 57 (11 December, 2006 19:17:07) Reply Quote More My Recent Posts Message Me Connection Blocking Invite Ignore User's Posts	hi matt, everybody is welcome. i just give you the code for example january, you fill at the special day the form, go to the vet, collecting the blood and send or to the netherlands or to the usa directly. we send to netherlands, because the post is much cheaper. for the usa we send from germany with fedex (they are the only one, who are allowed to send blood over there) fedex costs you about 70 pound from germany to usa. but it is very quick. i helped a breeder the other day, he wanted to test 5 dogs (so 100 euros is not the question), and wanted the result quick. so he sent direct to optigen (usa) at thursday and friday he had the confirming mail from optigen "everything arrived savedly" kind regards evelyn
Evelyn	Re: Optigen Testing	#15	[-]
Posts: 57 (11 December, 2006 19:21:11) Reply Quote More My Recent Posts Message Me Connection Blocking Invite Ignore User's Posts	*Quote:* I have just posted this in the Misc. section - I wonder if the DNAtag screen is the same as or equivalent to the optigen test? p211.ezboard.com/fgundogandbirddogforumsfrm19.showMessage?topicID=259.topic i think this is dna profiling lg evelyn
canburne	Re: Optigen Testing	#16	[-]
Posts: 474 (11 December, 2006 20:19:35) Reply Quote More My Recent Posts Message Me Connection Blocking Invite Ignore User's Posts	Hi Evelyn, if you drill further down into the website they offer screening for the following: # Phosphofructokinase Deficiency # Canine Phosphofructokinase Deficiency # Progressive Retinal Atrophy # Cystinuria # Globoid Cell Leukodystrophy they also offer a platinum service which screens for: # Globoid Cell Leukodystrophy # Neuronal Ceroid-Lipofuscinosis # Canine Beta-Glucuronidase # Multifocal Renal Cystadenocarcinoma And Nodular Dermatofibrosis # Progressive Retinal Atrophy # Canine Leukocyte Adhesion Deficiency # Col4a5 In X-Linked Hereditary Nephritis, # Phosphofructokinase Deficiency # Cystinuria # GM1 Gangliosidosis # Thrombasthenic Thrombopathia # Ceroid Lipofuscinosis # Shaking Puppy Syndrome # Cone Dysplasia # Von Willebrand Disease # Mucopolysaccharidosis VII # Renal Cystadenocarcinoma # Epidermolysis Bullosa # Malignant Hyperthermia # Severe Combined Immunodeficiency Syndrome # Dominant PRA # Myotonia Congenita # Haemophillia B # Von Willebrand Disease
Evelyn	Re: Optigen Testing	#17	[-]
Posts: 57 (11 December, 2006 20:36:31) Reply Quote More My Recent Posts Message Me Connection Blocking Invite Ignore User's Posts	oh sorry haven`t seen that. on my knowledge is only optigen does the prcd pra of the labradors for now. lg evelyn
Evelyn	Re: Optigen Testing	#18	[-]
Posts: 57 (12 December, 2006 06:58:41) Reply Quote More My Recent Posts Message Me Connection Blocking Invite Ignore User's Posts	*Quote:* HI there could anyone be confirm that FTCH Aughacasla Sam of Drakeshead was a carrier. I was told this but he hasnt been tested so how would you find out? Andy Berrybraegundogs hi andy this is was mrs ommerli wrote. in fact her male braught a pra offspring and she was wondering, where that gene came from. her males name is "conneywarren spike" (aughacasla sam o.d. x glenbonnie of conneywarren). she asked the owner of glenbonnie to let her (optigen)test, and she is clear. and if you watch the lists i copied the link, we did not found any offspring tested clear. what could be a dog with no clear offspring?? i share a bitch after conneywarren spike with a friend, and she was as well tested carrier. this is nowadays not a big deal anymore, we choosed a n/c stud dog and made a litter. we tested the 6 puppies, 4 are clear und 2 carrier. what happend first, that all people did go with her untested bitches to the clear males, this is wrong for the bredding. now all people are going with their clear bitches to clear males, also this is wrong. in a litter one partner has to be clear, but never the choice should be the n/c pup or the n/c stud dog, but still the best pup and the best studdog " Beispiel der Identifikation eines PRA-Anlagetrgers # ohne Bekanntwerden eines einzigen an PRA-erkrankten Nachkommens Conneywarren Spike # ist OptiGen carrier und es gibt einen Nachkommen, der an PRA erkrankt ist. Als Spike carrier getestet wurde, suchte ich vergeblich in seiner Ahnentafel nach einem bekannten PRA-Anlagetrger. Nicht ein einziger Hund in 5 Generationen war als carrier bekannt! Entweder der Vater oder die Mutter musste jedoch carrier sein - aber welcher Elternteil war es? Ist oder war Aughacasla Sam of Drakeshead PRA-Anlagetrger? Wenn ja, so wrde dies fr die Zucht von Arbeitslinien-Labradors die Katastrophe bedeuten, wenn wir nicht den OptiGen-Test htten, denn Sam hat weit ber 1000 Nachkommen. Alle direkten Sam Nachkommen, die bis heute OptiGen getestet sind, sind carrier; Conneywarren Spike, Conneywarren Nip, Tasco Drachma und weitere ? Oder wir finden Enkel, die wiederum carrier getestet sind; und jetzt tauchen pltzlich aus Shnen, Tchtern oder Enkeln von Sam Flle von PRA auf: Abbotsross Flynn # (Optigen carrier April 2006) Vater: Craighorn Gary(Aughacasla Sam # x Lochmuir Bonnie) Mutter: Abbotsross Molly(Countryways Missile x Nora v.h. Wieselsche Veld) Alice of Meadow Frescia # (PRA-Nachkomme) Vater: Pocklea Remus(Haretor Mark x Drakeshead Gypsy) Mutter: Greenbriar Faith(Aughacasla Sam #x Mossbriar Wagtail) Conneywarren Faith # (Optigen carrier 2005) Vater: Craighorn Bracken #(Aughacasla Sam # x Lochmuir Bonnie) Mutter: Glen Bonnie of Conneywarren (Optigen clear) Drakeshead Garth # (PRA-Nachkomme 2006) Vater: Middlegate Dexter of Drakeshead (Haretor Mark x Pocklea Tide of Middlegate) Mutter: Dolycoed Kate of Drakeshead (Aughacasla Sam # x Styleside Semola) Drakeshead Victor of Cuttlestone # (PRA-Nachkomme) Vater: Aughacasla Sam of Drakeshead # Mutter: Middlebrook Chough of Drakeshead (Middlegate Dexter of Drakeshead x Bolleswood Bashful of Middlegate) Jutland Judy of Hultonwood # (PRA Nachkomme) Vater: Aughacasla Sam of Drakeshead # Mutter: Saxifrage Salamanzar Mousehall Zip # (PRA-Nachkomme) Vater: Aughacasla Sam of Drakeshead # Mutter: Mousehall Zirconia Rhypyker Eros of Hietsun #(Optigen carrier 2006) Vater: Greenbriar Viper of Drakeshead (Lafayette Tolley x Greenbriar Solitaire) Mutter: Bramble Brooks of Rhypyker (Styperson Grouse # x Rhypyker Lightning) Styperson Grouse # (PRA-Nachkommen) Vater: Aughacasla Sam of Drakeshead # Mutter: Skellorn Rosemary (Haretor Mark of Drakeshead x Haulwen Gypsy) " affected list http://www.retriever.biz/breed/PRAaffected.pdf carrier list http://www.retriever.biz/breed/PRAcarrier.pdf kind regards evelyn
Evelyn	Re: Optigen Testing	#19	[-]
Posts: 57 (12 December, 2006 07:01:11) Reply Quote More My Recent Posts Message Me Connection Blocking Invite Ignore User's Posts	*Quote:* and if you watch the lists i copied the link, we did not found any offspring tested clear. what could be a dog with no clear offspring?? we did not find any sam offspring tested clear sorry evelyn
blackgundog	optigen testing	#20	[-]
Posts: 671 (12 December, 2006 11:40:39) Reply Quote More My Recent Posts Message Me Connection Blocking Invite Ignore User's Posts	Crumbs, when you look at the lists of carriers and PRA affected dogs it makes quite scary reading. I would guess most of us have dogs related to those on the list at some point. Is Craighorn Bracken also a carrier? I couldn't work this out from the list. BGD

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